Born in Russia 1900, to German and American parents, he spent his working life in France, England and the United States.
He worked his way up to chief of photography of the French Vogue. In 1935 George moved to New York City where he did most of his work for Harper's Bazaar.
He published two art books on Greece and Egypt before relocating to Hollywood, where he earned his reputation by shooting glamorous portraits for the film industry.
Hoyningen-Huene was one of the most influential fashion photographers of his time. Using shadows and elaborates lighting, but also created characteristically ahead of its time open-air swimwear pictures.
He became a leading fashion photographer, noted for his cool, refined style and extraordinary use of light. Hoyningen was also one of the first photographers to take pictures of models from above, arranging their skits around them like an open fan. In addition to his fashion layouts, Hoyningen-Huene gained a reputation as a celebrity portraitist, making images of people as diverse as the movie's.
A year after leaving Harper's, in 1946, Hoyningen-Huene moved to Hollywood where he taught photography at the Edward Kaminksi School of Creative Photography and at the Art Center School in Pasadena, California. Hoyningen also worked as a color consultant to films. He published books of his travel photographs from Greece, Egypt, and Mexico in the late 1940s
Hoyningen-Huene was among the 20th century's most creative historical of fashion and society. He never returned to full-time photography after he moved to Hollywood in 1946, George Hoyningen-Huene died of a heart attack in Los Angeles, California in 1968.